Seroprevalence to Cytomegalovirus in the Bulgarian Population, 2003-2015
Abstract from Fourth National Congress of Virology with International Participation /Days of Virology in Bulgaria Sofia, May 18th - 20th, 2016
Liliya Iv. Ivanova
Microbiology and Virology, Faculty of Medicine, Medical University, Varna, Bulgaria
Laboratory of Clinical
Virology, St. Marina University Hospital, Varna, Bulgaria
The prevalence of cytomegalovirus (CMV) infections is
between 50% and 85% in adults in different parts of the world. Its epidemiology
varies between socioeconomic and age groups. Our retrospective study has been
performed to determine the seroprevalence of CMV in the general population in
Northeastern Bulgaria. Between 2003 – 2015, we estimated the prevalence of
individuals with antibodies to CMV using indirect enzyme-linked immunosorbent assay
to detect virus-specific IgG and IgM. The population sample included 7879
individuals of both sexes and different ages. The total seroprevalence of CMV
was determined as 78.4%.
The relative deal of acute CMV infections was determined as
22.8%. We analysed the proportion of CMV IgG and IgM by sex and/or age group.
The results of the study reveal that CMV infection is highly prevalent in the
population and occurs mainly in the first years of life.