Education and Research
Sectors of Medical laboratory assistant, Medical Colleage, Medical University,
Microbiology and Virology, Faculty of Medicine, Medical University, Varna.
patients with rheumatoid arthritis.
Department of Preclinical
and Clinical Sciences, Faculty of Pharmacy, Medical University, Varna.
is the first human oncogenic virus which is associated with Burkit’s lymphoma, spread
in Africa, and NPC, mostly in South China. During the primary infection,
especially if it appears during adolescent and shortly after, IM clinic is
developed. Several researches have established that people, that have had
clinically developed IM, have roughly three times higher risk of developing
Hodgkins’ lymphoma. The highest risk is during the first 3 years after the
EBVinfection, however the interval could be between six months and twenty
years. EBV is widely spread member of the Herpesviridae family. Data shows that
in more than 90% of the adults’ population of the world specific anti-VCA IgG
can be found. In different researches from Bulgaria the seroprevalence is
between 60% and 80%.
The goal of this
study is to establish the frequency of EBV amongst the population of Northeast Bulgaria.
1. To research the seroepidemiological status of the
population in Northeast Bulgaria.
2. To analyse the frequency of the laboratory confirmed IM.
methods: 5016 serum samples of people tested for numerous reasons for EBV have
been analysed for the period 2010-2015. People of age between 1month and 70+
years are split into sixteen age groups. 625 of them have been diagnosed with IM.
The samples have been tested using the ELISA method for detection of anti VCA, IgM
frequency of EBV amongst the population of Northeast Bulgaria is expected.